abstract：PURPOSE:To evaluate the clinical course after early surgical treatment with excision of retinal hemangioblastomas (RHs) before development of major complications. METHODS:Interventional case series of four eyes (four patients) with a peripheral RH that had not yet been treated by laser or cryotherapy prior to surgery....

journal_title：Acta ophthalmologica

authors： van Overdam KA,Missotten T,Kilic E,Spielberg LH

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:To test the validity of the eyesi surgical simulator as an assessment tool in a virtual reality vitreoretinal training programme. METHODS:In collaboration with an experienced vitreoretinal surgeon, a virtual vitreoretinal training programme was composed on the eyesi surgical simulator, software version 2.9.2 (...

journal_title：Acta ophthalmologica

authors： Vergmann AS,Vestergaard AH,Grauslund J

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:To perform in vivo imaging of the Schlemm's canal (SC) with anterior segment spectral-domain optical coherence tomography [AS-spectral-domain (SD)-OCT] and also to measure its biometric parameters including the SC length and SC area in patients with pseudoexfoliation (PEX) glaucoma. METHODS:Forty-one consecuti...

journal_title：Acta ophthalmologica

authors： Imamoglu S,Sevim MS,Alpogan O,Ercalik NY,Kumral ET,Pekel G,Bardak H

更新日期：2016-12-01 00:00:00

abstract：PURPOSE:To examine the prevalence of anisometropia of spherical refraction (AnisoSR), astigmatism (AnisoAST) and spherical equivalent (AnisoSE) and their associations with spherical refraction (SR), refractive astigmatism (AST), spherical equivalent (SE) and interocular differences of ocular biometric parameters among ...

journal_title：Acta ophthalmologica

authors： Pärssinen O,Kauppinen M,Kaprio J,Rantanen T

更新日期：2016-12-01 00:00:00

abstract：PURPOSE:To determine the spectrum of BEST1 mutations and to study the phenotype in Slovenian families with Best vitelliform macular dystrophy (BVMD) to identify genotype-phenotype correlations. METHODS:Twenty patients from five families underwent the ophthalmological examination including electrooculogram (EOG; N = 17...

journal_title：Acta ophthalmologica

authors： Glavač D,Jarc-Vidmar M,Vrabec K,Ravnik-Glavač M,Fakin A,Hawlina M

更新日期：2016-12-01 00:00:00

abstract：PURPOSE:To explore associations of lamina cribrosa thickness with axial length and thickness of the posterior sclera in monkeys. METHODS:Examining histological sections by light microscopy, we measured the thickness of the lamina cribrosa and posterior sclera and axial length. RESULTS:The study included 28 animals (2...

journal_title：Acta ophthalmologica

authors： Jonas JB,Kutscher JN,Panda-Jonas S,Hayreh SS

更新日期：2016-12-01 00:00:00

abstract：PURPOSE:To determine whether decreasing illumination of the Pelli-Robson contrast sensitivity (CS) chart and MP-1 microperimeter to low mesopic conditions is more sensitive to vision changes occurring with healthy ageing and in early and intermediate age-related macular degeneration (AMD) and whether these mesopic test...

journal_title：Acta ophthalmologica

authors： Maynard ML,Zele AJ,Feigl B

更新日期：2016-12-01 00:00:00

abstract：PURPOSE:The computer program laguna onhe determines optic nerve head haemoglobin (ONH Hb) on retinal photographs based on detecting colour differences. This study compares the diagnostic capacity of Laguna ONhE with that of spectral domain optical coherence tomography (OCT) and confocal tomography (HRT III). METHODS:I...

journal_title：Acta ophthalmologica

authors： Mendez-Hernandez C,Rodriguez-Uña I,Gonzalez-de-la Rosa M,Arribas-Pardo P,Garcia-Feijoo J

更新日期：2016-11-01 00:00:00

abstract：PURPOSE:To moderate the capsular opacification (CO) response after lens surgery, an experimental study was performed in which nanofibre-based hydrogels (nanogels) with different ratios of attached peptides were applied to provide extracellular matrix-related cues for lens epithelial cells (LECs) in a porcine eye model....

journal_title：Acta ophthalmologica

authors： Nibourg LM,Gelens E,Nibourg SA,de Jong MR,Kuijer R,van Kooten TG,Koopmans SA

更新日期：2016-11-01 00:00:00

abstract：PURPOSE:To investigate changes in retinal metabolism, function, structure and morphology in relation to initiation of insulin pump therapy (continuous subcutaneous insulin infusion, CSII). METHODS:Visual acuity, retinopathy level, dark adaptation kinetics, retinal and subfoveal choroidal thickness, macular perfusion v...

journal_title：Acta ophthalmologica

authors： Klefter ON,Hommel E,Munch IC,Nørgaard K,Madsbad S,Larsen M

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:To study high-resolution ultrasound biomicroscopy (UBM) findings in anterior scleral inflammatory disease and evaluate the efficacy of high-resolution UBM as an adjunctive diagnostic tool. METHODS:A cross-sectional study. The medical records of 30 patients (33 eyes) with episcleritis or anterior scleritis were...

journal_title：Acta ophthalmologica

authors： Zur D,Neudorfer M,Shulman S,Rosenblatt A,Habot-Wilner Z

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:Elevated intra-ocular pressure (IOP) has been identified as a major risk factor for glaucoma. Additionally, extensive literature depicts a vascular dysfunction to exist in these patients. However, a large ocular blood flow-oriented trial to integrate these findings in the clinical setting is lacking. This study...

journal_title：Acta ophthalmologica

authors： Abegão Pinto L,Willekens K,Van Keer K,Shibesh A,Molenberghs G,Vandewalle E,Stalmans I

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:To compare changes in macular pigment optical density (MPOD) and serum lutein concentration between free lutein and lutein esters supplements in healthy Japanese individuals. METHODS:Twenty healthy subjects (age range, 22-47 years) were recruited into this prospective, randomized, doubled-blind comparative stu...

journal_title：Acta ophthalmologica

authors： Yoshizako H,Hara K,Takai Y,Kaidzu S,Obana A,Ohira A

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:To report the indications and the outcomes of keratoplasties in children over four decades. METHODS:A retrospective cohort study of patients aged 16 years or younger who underwent keratoplasty in the Helsinki University Eye Hospital during 1968-2011. Diagnosis, preoperative status, age at the time of surgery, ...

journal_title：Acta ophthalmologica

authors： Majander A,Kivelä TT,Krootila K

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:To study the connection between parental myopia and their children's myopia from school age to adulthood. METHODS:Two hundred and forty myopic schoolchildren (119 boys, 121 girls, mean age 10.9 years) with no previous spectacles for myopia were recruited to a 3-year treatment trial with different use of specta...

journal_title：Acta ophthalmologica

authors： Pärssinen O,Kauppinen M

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:Clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma has been reported. We, therefore, investigated the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE in a cell culture model. METHODS:The e...

journal_title：Acta ophthalmologica

authors： Süsskind D,Hagemann U,Schrader M,Januschowski K,Schnichels S,Aisenbrey S

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:To investigate risk factors for the development of the hypertensive phase after implantation of the Ahmed glaucoma valve (AGV). METHODS:A total of 128 patients who had undergone AGV implantation were included in this study. The hypertensive phase was defined as intraocular pressure (IOP) > 21 mmHg during the f...

journal_title：Acta ophthalmologica

authors： Jung KI,Park CK

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy and safety of the ultrasonic circular cyclocoagulation procedure in patients with open-angle glaucoma naïve of previous filtering surgery. METHODS:Prospective non-comparative interventional clinical study conducted in five French University Hospitals. Thirty eyes of 30 patients with op...

journal_title：Acta ophthalmologica

authors： Aptel F,Denis P,Rouland JF,Renard JP,Bron A

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:To investigate incidence, clinicopathological features and prognosis of BRAF-mutated conjunctival melanoma in Denmark. Furthermore, to determine BRAF mutations in paired premalignant lesions and evaluate immunohistochemical BRAF V600E oncoprotein detection. METHODS:Data from 139 patients with conjunctival mela...

journal_title：Acta ophthalmologica

authors： Larsen AC,Dahl C,Dahmcke CM,Lade-Keller J,Siersma VD,Toft PB,Coupland SE,Prause JU,Guldberg P,Heegaard S

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:Monthly dosing with ranibizumab (RBZ) is needed to achieve maximal visual gains in patients with neovascular ('wet') age-related macular degeneration (wAMD). In Sweden, dosing is performed as needed (RBZ PRN), resulting in suboptimal efficacy. Intravitreal aflibercept (IVT-AFL) every 2 months after three initia...

journal_title：Acta ophthalmologica

authors： Panchmatia HR,Clements KM,Hulbert E,Eriksson M,Wittrup-Jensen K,Nilsson J,Weinstein MC

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:Keratoconus is a progressive disorder and one of the primary indications for corneal transplantation. Anterior lamellar keratoplasty offers several advantages over other techniques, including endothelial preservation and longer graft survival. In this study, we examined the recent trend of using lamellar techni...

journal_title：Acta ophthalmologica

authors： Godefrooij DA,Gans R,Imhof SM,Wisse RP

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:To investigate the value of posterior keratometry in the assessment of surgically induced astigmatic change (AC) in cataract surgery, with particular emphasis on the influence of test-retest variability. METHODS:Seventy-seven eyes of 77 cataract patients scheduled for routine cataract surgery were enrolled. Al...

journal_title：Acta ophthalmologica

authors： Klijn S,van der Sommen CM,Sicam VA,Reus NJ

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:To present clinical results regarding the treatment of patients with age-related macular degeneration (neovascular form) after the implementation of a 'virtual' type of follow-up in a single retina service centre. METHODS:Retrospective study based on the clinical records of the Leicester Royal Infirmary Retina...

journal_title：Acta ophthalmologica

authors： Tsaousis KT,Empeslidis T,Konidaris VE,Kapoor B,Deane J

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:To evaluate the biomechanical properties of the cornea using Corneal Visualization Scheimpflug Technology (CorVis ST, Oculus) in eyes with primary open-angle glaucoma (POAG) and normal control eyes. METHODS:A comparative cross-sectional study that included 42 patients with POAG and 60 normal control subjects m...

journal_title：Acta ophthalmologica

authors： Tian L,Wang D,Wu Y,Meng X,Chen B,Ge M,Huang Y

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:Eyelid sebaceous carcinoma (SC) remains a common diagnostic pitfall for both the clinician and histopathologist. The aim of this study was to describe perforin as a new marker in the immunohistochemistry panel for SC. METHODS:A total of 29 cases were retrieved from the Pathology archives, including 11 sebaceou...

journal_title：Acta ophthalmologica

authors： Mittal R,Araujo I,Czanner G,Coupland SE

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:To examine the influence of experimentally reduced cerebrospinal fluid pressure (CSFP) as compared to elevated intraocular pressure (IOP) on axonal morphology and axonal motor proteins in retinal ganglion cells (RGCs). METHODS:The experimental study included 39 rats which underwent cerebrospinal fluid drainage...

journal_title：Acta ophthalmologica

authors： Zhang Z,Wu S,Jonas JB,Zhang J,Liu K,Lu Q,Wang N

更新日期：2016-05-01 00:00:00

abstract：PURPOSE:To explore whether the prevalence and severity of retinopathy differ in diabetes cohorts diagnosed through screening as compared with conventional health care. METHODS:A total of 257 diabetes patients, 151 detected through screening and 106 through conventional clinical care, were included. Retinopathy was eva...

journal_title：Acta ophthalmologica

authors： Olafsdottir E,Andersson DK,Dedorsson I,Svärdsudd K,Jansson SP,Stefánsson E

更新日期：2016-05-01 00:00:00

abstract：PURPOSE:To report the postoperative results after enucleation of using an acrylic orbital implant covered in donor sclera for implantation. METHODS:We retrospectively analysed the charts of patients who were enucleated between 2007 and 2011. Only patients who received an acrylic implant covered with donor sclera were ...

journal_title：Acta ophthalmologica

authors： Jongman HP,Marinkovic M,Notting I,Koetsier L,Swart W,Schalij-Delfos NE,Bleeker J,Jager MJ,Luyten GP

更新日期：2016-05-01 00:00:00

abstract：:Surgical approaches for rhegmatogenous retinal detachment (RRD) have evolved rapidly in the past century. This has resulted in an increase in the anatomical success rate from zero per cent in the beginning of the 1900s to now almost 100 per cent. Rhegmatogenous retinal detachment is regarded as an acute eye disease th...

journal_title：Acta ophthalmologica

authors： Hajari JN

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:To evaluate the outcome of a prospective protocol for the treatment of chronic central serous chorioretinopathy (CSC). METHODS:Interventional prospective case series in 59 eyes (59 patients) with active chronic CSC. All patients were first treated with indocyanine green angiography (ICGA)-guided half-dose phot...

journal_title：Acta ophthalmologica

authors： Breukink MB,Mohr JK,Ossewaarde-van Norel A,den Hollander AI,Keunen JE,Hoyng CB,Boon CJ

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of big-bubble (BB) technique in separating Dua's layer together with the Descemet's membrane endothelial (DE) graft and the effect of 7-day storage of the prepared tissues on the endothelial cells. METHOD:This is an experimental study in which 21 human corneo-scleral tissues unsuitable...

journal_title：Acta ophthalmologica

authors： GamalElDin SA,Salama MM,ElShazly MI

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:To indirectly measure stromal riboflavin penetration using commercially available riboflavin solutions and new and existing epithelium-off, trans-epithelial and iontophoresis-assisted delivery protocols. METHODS:Forty porcine eyes were divided into eight groups. Group 1: Ricrolin applied to the de-epithelialis...

journal_title：Acta ophthalmologica

authors： Hayes S,Morgan SR,O'Brart DP,O'Brart N,Meek KM

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:To assess the agreement between a Scheimpflug camera (Pentacam) and a combined Placido-optical coherence tomography device (Visante OMNI) in measuring corneal curvature, thickness and elevation values in normal and keratoconic eyes. METHODS:Corneal measurements of 110 normal eyes (one eye per subject) and 70 k...

journal_title：Acta ophthalmologica

authors： Viswanathan D,Kumar NL,Males JJ,Graham SL

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:Previous studies have indicated that the immune system is involved in the pathogenesis of the AMD. Increased visceral fat, in addition, has a pro-inflammatory effect on the organism by producing or influencing different kinds of inflammatory factors. The aim of this study is to determine the relationship of bod...

journal_title：Acta ophthalmologica

authors： Haas P,Kubista KE,Krugluger W,Huber J,Binder S

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:Proliferative diabetic retinopathy (PDR) is characterized by ischaemia- and inflammation-induced neovascularization, but the pathological vascular differentiation in PDR remains poorly characterized. Here, endothelial progenitor and growth properties, as well as potential lymphatic differentiation, were investi...

journal_title：Acta ophthalmologica

authors： Loukovaara S,Gucciardo E,Repo P,Vihinen H,Lohi J,Jokitalo E,Salven P,Lehti K

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:To investigate and analyse one hundred-year-old endothelial cells of human transplanted corneal grafts and compare them with intact endothelium of unoperated eyes. SUBJECTS AND METHODS:Specular microscopy was performed on seven individuals (14 eyes) aged >100 years and on seven transplanted corneas with endoth...

journal_title：Acta ophthalmologica

authors： Ruusuvaara P,Vesti E,Koskela E,Setälä K

更新日期：2015-09-01 00:00:00

abstract：:Endoscopic Cyclophotocoagulation (ECP) is a glaucoma surgery designed to reduce the intraocular pressure (IOP) by partially ablating the ciliary processes to decrease aqueous humour production and secretion. The aim of this paper is to review the literature regarding the background, indications and results of the surg...

journal_title：Acta ophthalmologica

authors： Kaplowitz K,Kuei A,Klenofsky B,Abazari A,Honkanen R

更新日期：2015-08-01 00:00:00

abstract：PURPOSE:To evaluate the EyeSi(™) simulator in regard to assessing competence in cataract surgery. The primary objective was to explore all simulator metrics to establish a proficiency-based test with solid evidence. The secondary objective was to evaluate whether the skill assessment was specific to cataract surgery. ...

journal_title：Acta ophthalmologica

authors： Thomsen AS,Kiilgaard JF,Kjaerbo H,la Cour M,Konge L

更新日期：2015-08-01 00:00:00

abstract：PURPOSE:To compare pars plana vitrectomy and 360° endolaser therapy with pars plana vitrectomy and an encircling scleral buckle for the treatment of primary rhegmatogenous retinal detachments in a randomized pilot study including 60 patients. METHODS:Main outcome measures were single-surgery anatomic success rate and ...

journal_title：Acta ophthalmologica

authors： Falkner-Radler CI,Graf A,Binder S

更新日期：2015-08-01 00:00:00

abstract：PURPOSE:To evaluate the safety and efficacy of 1.5% dexamethasone nanoparticle (DexNP) drops in eyes with non-infectious uveitic macular oedema and vitritis. METHODS:In a prospective pilot study, DexNP drops were administered four times a day for 4 weeks followed by drops tapering over a period of another 4 weeks. Fol...

journal_title：Acta ophthalmologica

authors： Shulman S,Jóhannesson G,Stefánsson E,Loewenstein A,Rosenblatt A,Habot-Wilner Z

更新日期：2015-08-01 00:00:00